Guide · Ingredient × Concern
Vitamin B3 for melasma.
Vitamin B3 for melasma — what the science actually says, what concentration is therapeutic, and which products in the Uwazia catalog pair the two. Evidence grade: moderate.
What the evidence says
Moderate evidence.
Several studies support the claim, with some inconsistency in conditions or outcomes.
That's our honest grade — not a marketing claim.
The science
What's actually happening.
How vitamin b3 works
Inhibits melanosome transfer from melanocytes to keratinocytes; supports ceramide synthesis; regulates sebum production.
Full ingredient pageWhat melasma is
Acquired hyperpigmentation, typically symmetrical on cheeks, forehead, upper lip. Hormonally and UV-driven. Often persistent and recurrent.
Full concern pageWhat to look for
Reading a label for vitamin b3.
Therapeutic range
2–10%
Concentrations supported by clinical literature. Below this range, the active is functionally cosmetic.
Sun exposure
Not photosensitizing.
Safe under daily SPF. UV protection remains essential for any pigmentation work.
Watch for
- Mild flushing at concentrations above 5% (rare)
Products · 1
Products that pair vitamin b3 with melasma.
Related guides
Adjacent pairings worth reading.
Other ingredients for melasma
Other concerns vitamin b3 addresses